People

Principal Investigator

      Xiaozhou Luo is a professor and executive director at Center for Synthetic Biochemistry (CSB), Institute of Synthetic Biology (iSynBio), Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences.
      Dr. Luo received his Bachelor degree from Nanyang Technological University in 2010, and PhD in chemistry from The Scripps Research Institute in 2016. He was a post-doctoral fellow at Jay D. Keasling’s lab at the University of California, Berkeley before joining SIAT.
      He is mainly engaged in the innovative research of synthetic biology of natural products and the directed evolution of enzymes. His work has been published in Nat Chem Biol, Cell Chem Biol, Proc Natl Acad Sci USA, Angew Chem Int Ed and other top international academic journals.

Assistant Professors & Postdocs

Qiaoli Liu (刘巧利)

Email:ql.liu@siat.ac.cn 

Education

PhD, 2012.09 – 2018.12, Jiangnan University, Prof. Zhiming Rao

MSc, 2006.09 – 2009.06, Northwest A&F University, Prof. Gehong Wei

BS, 2002.09 – 2006.06, Xinjiang University

Work Experience

PostDoc, 2019.04 – 2023.02, SIAT, Prof. Xiaozhou Luo

R&D Engineer, 2009.08 – 2012.02, Shandong BaoLaiLiLai Biological Engineering co. LTD

Research Fields: Biosynthesis of unnatural amino acids.

Yunfeng Zhang (张云丰)

Email:yf.zhang@siat.ac.cn 

Education

PhD, 2013-2019, Jiangnan University (Prof. Guocheng Du)

Visiting Scholar, 2017-2019, University of California at Berkeley (Pro. Jay D. Keasling)

BS, 2009-2013 Inner Mongolia Normal University (Prof. Min Li)

Work Experience

Assistant professor, 2021- present, SIAT (Pro. Xiaozhou Luo & Jay D. Keasling)

Post doctor, 2019-2021, SIAT (Pro. Xiaozhou Luo & Jay D. Keasling)

Research interest: Engineering yeast chassis to produce terpenoids; Direct evolution of enzymes for specific reactions.

Huaxiang Deng(邓华祥)

Email:hx.deng@siat.ac.cn

Education

PhD, 2012 – 2019, Jiangnan University (Prof. Yujie Cai)

Visiting PhD student, 2018 – 2019, University of California, at Berkeley (Prof. Jay D. Keasling)

BS, 2008 – 2012, Sichuan University of Science & Engineering (Prof. Dan Huang)

Work Experience

Assistant professor, 2021 – present, SIAT (Prof. Xiaozhou Luo and Jay D. Keasling)

PostDoc, 2019 – 2021, Jiangnan University (Prof. Yujie Cai)

Research interest: An efficient chemical platform in E. coli by biofoundry-assisted pathway debottlenecking

Jing Liang(梁菁)

Email:jing.liang@siat.ac.cn

Education

PhD, 2013.08 – 2018.10, Virginia Polytechnic Institute and State University, Blacksburg, USA (Prof. Jianyong Li).

MSc, 2010.09 – 2013.07, State Key Laboratory of Genetic Engineering, Fudan University, Shanghai, China (Prof. Juan Lin)

BS, 2006.09 – 2010.07, College of Life Sciences, Northwest University, Xi’an, China

Work Experience

PostDoc, 2019.12-present, SIAT (Xiaozhou Luo)

Practical training, 2018.10 – 2019.10, Virginia Polytechnic Institute and State University, Blacksburg, USA

Reasearch interest:

Xinran Wang(王欣然)

Email:xr.wang@siat.ac.cn

Education & work experience:

2020-now, SIAT, Keasling and Luo lab

PhD&PostDoc, 2012-2020, Shanghai Jiao Tong University, Prof. Linquan Bai’s lab;

BS&MSc, 2005-2012, Shandong University, Prof. Qingsheng Qi’s lab;

Research direction: Development of engineering tools for streptomyces chassis

Lingfeng Zhu(朱凌峰)

Email:zhulf@siat.ac.cn

Education

PhD, 2016.09 – 2020.06, Heinrich Heine University Düsseldorf (Prof. Michael Bott)

MSc, 2012.09 – 2016.01, Institute of Microbiology, Chinese Academy of Sciences (Prof. Bo Yu)

BS, 2008.09 – 2012.06, China University of Mining and Technology, Beijing

Work Experience

Assistant professor, SIAT (Prof. Xiaozhou Luo and Prof. Jay D. Keasling)

PostDoc, 2020-2022, SIAT (Prof. Xiaozhou Luo and Prof. Jay D. Keasling)

Research Interest:

Pan Zhang(张盼)

Email:pan.zhang@siat.ac.cn

Education

PhD, 2013.09-2020.06, China Agricultural University (Prof. Wenxin Chen and Prof. Changfu Tian)

BS, 2009.09-2013.06, Tianjin Agricultural University

Work Experience

Assistant professor, 2023.03- present, SIAT (Prof. Xiaozhou Luo)

PostDoc, 2020.07-2023.03, SIAT (Prof. Xiaozhou Luo)

Research Interest: Biosynthesis and Application of Unnatural Amino Acids

Yang Zhang(张洋铭)

Email:ym.zhang@siat.ac.cn

Education

MD, 2017.09-2020.06, Peking University (Prof. Changtao Jiang)

BS, 2012.09-2017.06, Peking University

Work Experience

Assistant professor, 2022.08- present, SIAT (Prof. Xiaozhou Luo)

PostDoc, 2020.08-2022.08, SIAT (Prof. Xiaozhou Luo)

Research interest: Commensal microbiome and human diseases; AI-based discovery on multi-omics.

Tongjian Yang(杨统见)

Email:tj.yang@siat.ac.cn

Education

PhD, 2013-2020, Institute of Microbiology, Chinese Academy of Sciences (Prof. Yihua Chen and Prof. Keqian Yang).

Research interest

Assistant professor, 2022-present, SIAT (Prof. Jay Keasling and Prof. Xiaozhou Luo)

PostDoc, 2020-2022, SIAT (Prof. Jay Keasling and Prof. Xiaozhou Luo)

Reasearch area:

My primary research aims to develop an automated platform for creating industrial microbial chassis that are more efficient and streamlined, with the goal of making it easier to discover bioactive secondary metabolites through high-throughput mining.

Haibing He (何海兵)

Email: hb.he@siat.ac.cn

Education
2016 – 2020, PhD, Graduate School of Pharmaceutical Sciences, The University of Tokyo; Supervisor: Prof. Ikuro Abe

2013 – 2016, MSc, Ocean College, Zhejiang University, China; Supervisor: Prof. Zhongjun Ma

2009 – 2013, BS, Jilin University, China

Work Experience

2022 – present, Senior Research Associate, SIAT, Prof. Xiaozhou Luo

2020 – 2022, Postdoctoral Research Associate,  Supervisor: Prof. Xiaozhou Luo

Research Interest: Enzyme engineering and metabolic engineering

Zhibo Li (黎志波)

Email: lizb@siat.ac.cn

Education:

PhD, 2015.12-2020.8, University of Groningen, the Netherlands, Molecular Genetics group, Prof. Oscar P. Kuipers

MSc, 2013.9-2015.7, China Agricultural University, Plant nutrition, Prof. Lixing Yuan

BS, 2009.9-2013.7, Northwest Agricultural & Forestry University, Resources and Environmental Science

Work experience:

Assistant Professor, 2022.12-present, SIAT, Keasling&Luo lab

PostDoc, 2020.12-2022.11 postdoc, SIAT, Keasling&Luo lab

Research interest: Heterologous expression of secondary metabolite BGCs.

Yun Liu (刘云)

Email: yun.liu@siat.ac.cn

Education

PhD, 2016.09-2020.12, Huazhong Agricultural University, Horticulture, Supervisor, Prof. Xiuxin Deng

MSc, 2014.09-2016.06, Huazhong Agricultural University, Horticulture, Supervisor, Prof. Xiuxin Deng

BS, 2010.09-2014.06, Shanxi Agricultural University

Work Experience

PostDoc, 2021.05-present, SIAT, Prof. Xiaozhou Luo

Research: Synthetic biology of microorganisms, and discovery, biosynthesis and evolution of plant natural products

Yaying Xu (徐亚英)

Email:yy.xu2@siat.ac.cn

Education

PhD, 2017.09-2023.01, East China University of Science and Technology (Prof. Zhimin Li)

BS, 2009.09-2013.06, Jiangsu Ocean University

Work Experience

PostDoc, 2023.02-present, SIAT (Prof. Xiaozhou Luo)

Research Interest: Metabolic engineering yeast chassis for terpenoid product.

Liufang Huang (黄柳芳)

Email: yun.liu@siat.ac.cn

Education

PhD, 2019.9-2022.7, School of Pharmaceutical Sciences, Guangzhou University of Chinese medicine, Supervisor: Prof. Lixin Duan, Prof. Zhongqiu Liu

MSc, 2014.9-2017.7, School of traditional Chinese medicine, Guangdong Pharmaceutical University, Supervisor: Prof. Shengguo Ji

BS, 2010.9-2014.7, College of pharmacy, Shaanxi University of Chinese medicine

Work Experience

Manager, 2017.7-2019.5, Technology and Business Department, Guangzhou University City Health Industry Technology Park Investment Management Co., Ltd

Chinese medicine researcher, 2022.8-2023.8, Key Laboratory of TCM Clinical Pharmacy, Shenzhen Baoan Authentic TCM Therapy Hospital, Shenzhen, Guangdong

PostDoc, 2023.08-present, SIAT,  Keasling&luo lab

Research Interest: Biosynthesis of natural products

Ziyan He (何子岩)

Email: zy.he@siat.ac.cn

Education

PhD, 2020.09-2023.06, IOCAS, Supervisor, Prof. Nansheng Chen

MSc, 2017.09-2020.06, Ocean University of China, Supervisor, Prof. Luqing Pan

BS, 2013.09-2017.06, Ocean University of China

Work Experience

PostDoc, 2023.09-present, SIAT, Prof. Xiaozhou Luo

Research Interest: Genome mining of terpene biosynthesis gene clusters

Graduate Students

Yanling Wu(吴燕玲)
PhD Student

Email: yl.wu@siat.ac.cn

Education

PhD, 2021.09 – present, University of Chinese Academy of Sciences (Prof. Xiaozhou Luo).

Research Interest: Biosynthesis of triterpenoids in Saccharomyces Cerevisiae

Shumin Lin (林淑敏)
PhD Student

Email: sm.lin1@siat.ac.cn

Education

PhD, 2023.09 – present, University of Chinese Academy of Sciences (Prof. Xiaozhou Luo).

BS & MSc, 2014.09 – 2021.06, Guangzhou University of Chinese Medicine (Prof. Hui Xu).

Research Interest: De novo biosynthesis of natural products

Yan Chen (陈燕)
Master Student

Email: y.chen@siat.ac.cn

Education

MSc, 2022.7 – present, University of Chinese Academy of Sciences

BS, 2018.9 – 2022.6, Dalian University of Technology

 

Research Interest: Biosynthesis of terpene and terpenoids using Saccharomyces Cerevisiae

Visiting Scholars

Xingyan Sun (孙兴妍)
Postdoc

Email: sunxingyan@szbl.ac.cn

Education

PhD, 2020.9-2023.6, Institute of Materia Medica, Chinese Academy of Medical Science & Peking Union Medical College (Prof. Dongming Zhang).

Msc, 2017.9-2020.6, Institute of Materia Medica, Chinese Academy of Medical Science & Peking Union Medical College (Prof. Dongming Zhang).

BS, 2013.9-2017.7, Shenyang Pharmaceutical University.

Work Experience

PostDoc, 2023.07-present, SZBL & SIAT, Prof. Xiaoyu Tang & Prof. Xiaozhou Luo

Research Interest: Terpene biosynthesis of corals based on genome mining

Biming Zhong(钟必鸣)
PhD Student

Email: bm.zhong@siat.ac.cn

Education

PhD, 2023.09-present, The Hong Kong Polytechnic University (PolyU) (Prof. Xiaozhou Luo).

MSc, 2018.02 – 2019.12, The University of Melbourne (Dr. Hafiz A.R. Suleria)

BS, 2015.09 – 2017.12, Deakin University

BS, 2013.09 – 2018.09, Dalian Polytechnic University

Research Interest: Data storage using peptides in an E.coli expression system; Interspecies interactions of gut microbiota using multi-omics

Linlin Xu(徐林琳)
PhD Student

Email: ll.xu@siat.ac.cn

Education

PhD, 2021 – present, Northeast Forestry University

BS, 2017 – 2021, Northeast Forestry University

Research Interest: Regulation and synthesis of plant natural products

Shumei Ye(叶书梅)
PhD Student

Email: sm.ye@siat.ac.cn

Education

PhD, 2021.09-present, Inner Mongolia University (Prof. Xiaozhou Luo).

MSc, 2015.09-2018.06, Sichuan Agricultural University (Prof. Li ping)

Work Experience

Lecturer, 2015.10 – present, Inner Mongolia Medical University, College of Basic Medicine

Research Interest: Function of gut microbiota

Qianying Zhou(周倩影)
Master Student

Email: qy.zhou@siat.ac.cn

Education

MSc, 2022.09 – present, The Institute of Plant Protection,Chinese Academy of Agricultural Sciences

Research Interest: Microbial natural product pesticides, Agricultural antibiotics, Natural products of Streptomyces

Jiaqi Wang(王家琦)
Master Student

Email: jq.wang3@siat.ac.cn

Education

MSc, 2022.9 – present, Kashi University

BS, 2018.9 – 2022.7, Wuhan Institute of Technology

Research Interest: High yield of natural products of Streptomyces

Research Assistants

Ningxin Chen (陈宁辛)

Email: nx.chen1@siat.ac.cn

Education

MSc, 2016 – 2020, Soochow University, Microbiology, Hin-chung Wong

Work Experience

Research Assistant, 2021 – present, SIAT

Research Interest: Pan-genomic analysis in streptomyces species for development of engineering tools

Banlai Ruan(阮班来)

Email: bl.ruan@siat.ac.cn

Education

MSc, 2016.9-2019.7, China Medical University

BS, 2012.9-2016.7, Wuchang University of Technology

Work Experience

Research Assistant, 2021.05- present, SIAT

Research Assistant, 2019.10- 2021.05, The Affiliated Hospital of Northwest University

Research Interest: Synthetic biology, Basic medicine, AI-Drug

Mixian Zhao (赵米贤)

Email: mx.zhao@siat.ac.cn

Education

MSc, 2020 – 2022, China Agricultural University

Work Experience

Research Assistant, 2022 – present, SIAT

Research Interest: Function of gut microbiota

Ziyou Wu(吴子悠)

Email: ziyou.wu@siat.ac.cn

Education

MSc, 2021.09-2022.09, University of Glasgow

BS, 2016.09-2020.07, Henan Agricultural University

Work Experience

Research Assistant, 2022 – present, SIAT

Research Interest: Function of gut microbiota in diseases

Ting Feng(冯婷)

Email: @siat.ac.cn

Education

MSc, 2021.09-2023.06, Anhui Agricultural University

BS, 2017.09-2021.06, Shanxi Agricultural University

Work Experience

Research Assistant, 2023.06 – present, SIAT, Keasling&Luo lab

Research Interest: Synthetic Biology

Shiquan Fu(符士泉)

Email: sq.fu@siat.ac.cn

Education

MSc, 2020.09-2023.07, Shenzhen University

BS, 2015.09-2019.07, Guangdong University of Technology,

Work Experience

Research Assistant, 2023.07 – present, SIAT

Research Interest: Heterologous expression of secondary metabolite BGCs.

Engineers

Yulan Qiu(邱玉兰)

Email: yl.qiu@siat.ac.cn

Education

BS, 2011.09 – 2015.06, Zhejiang Wanli University

Work Experience

Engineer, 2020.06 – present, SIAT (Luo Lab)

2017.05 – 2020.03, iCarbonX

Research Interest: Next-generation sequencing & Automation

Technicians

Dadeng Zhang(张达登)

Email: dd.zhang@siat.ac.cn

Education

MSc, 2018.09 – 2022.06, Yunnan Agricultural University

Work Experience

Technician, 2022.06 – present, SIAT (Luo Lab)

Intern, 2020.07 – 2020.10, Institute of Medicinal Plants, Yunnan Academy of Agricultural Sciences, Li Shuhong Group

Intern, 2020.11 – 2020.03, Institute of Biotechnology and Germplasm Resources, Yunnan Academy of Agricultural Sciences, Wang Li Group

Intern, 2021.04 – 2021.08, Kunming Institute of Botany, Chinese Academy of Sciences, Wang Xianghua Group

Research Interest: Excavation of Sanghuang PKS gene cluster, construction of Pichia CRISPR system, etc.

Jiahui He(何佳慧)

Email: jh.he2@siat.ac.cn

Education

BS, 2018.09-2022.06, Hunan University of Science and Engineering

Work Experience

Technician, 2022.08 – present, SIAT (Keasling &Luo Lab)

Research Interest: Create a high-value-added chassis with the help of synthetic biology technology

Kailong Chen(陈凯龙)

Email: kl.chen@siat.ac.cn

Education

BS, 2018.09-2022.06, Zhaoqing University, Pharmaceutical Engineering

Work Experience

Synthesis Technician, 2022.06-2022.12, Guangzhou RiboBiotechnology Co., Ltd;

Technician, 2022.12 – present, SIAT (Luo Lab)

Research Interest: 

Administrative Assistant

Zhenqin Wei(魏珍琴)
Nanchang Institute of Technology, Business Administration
Accounting Direction

Alumni

Associate Professor

 Hongting Tang(汤红婷)

Postdoctoral Fellows

Xixi Zhao(赵西西)
University of California, Berkeley

Jiazeng Yang(杨加增)

Dr. Shengli Zhuang(庄胜利)
Dr. Dan He(何丹)
Dr. Que Chen(陈鹊)
Dr. Yin Zhang(张尹)
Dr. Ruidong Chen(陈瑞东)
Dr. Xiaoxue Zhou(周小雪)

Research Assistants

Shengtao Bo(薄胜涛)
Huan Lu(卢欢)
Shasha Li(李沙沙)

Tingye Feng(冯庭叶)

Nanzhu Chen(陈南柱)

University of Hong Kong
Doctoral student

Jiliang Deng(邓吉良)

WuHan University
Doctoral student

Changle Zhao(赵长乐)
Tianjin University
Doctoral student

Dawei You(尤大伟)

Peking University
Doctoral student

Yimeng Cui (崔一萌)
Xufan Lian(廉旭凡)
Yufei Chen(陈俞妃)
Ce Dong(董策)
Yanwu Deng(邓艳午)
Jing Wang(王景)
Rui Di(狄睿)

Graduate Students

Han Yu(余函)

Li Feifei (李菲菲)

Visiting Scholars

Weiyue Liang(梁维悦)
Jiangnan University
Master student

Yamin Lin(林亚敏)
Institute of Microbiology, CAS – Doctoral Student

Zexin Wang (王泽新)

Lijuan Liu (刘丽娟)
HongKong University

Donyi Liu (刘冬艺)
HongKong University

Shuo Yang (杨硕)

Yanan Qiao(乔亚南)

Shihao Mei(梅世豪

Xiyan Zhang (张希妍)

Technicians

Zhaohui Zheng(郑兆辉)

Haolin Luo (罗浩林)
Shenzhen University
Master Student

Yuxian He (何雨贤)
Zao Zhuang University, Biotechnology

Qiuchi Song (宋秋池)

Engineers​

Junfeng Shen(沈俊峰)