Publications

# denote co-first authorship, * denote co-corresponding/co-senior authorship.


At SIAT

2021
25. Wang, Y., Chen, X., Cai, W., Tan, L., Yu, Y., Han, B., Li, Y., Xie, Y., Su, Y., Luo, X. and Liu, T., 2021. Expanding the Structural Diversity of Protein Building Blocks with Noncanonical Amino Acids Biosynthesized from Aromatic Thiols. Angewandte Chemie, 133(18), pp.10128-10136.


2020
24. Hu, R.#, Zhang, S.#, Meng, H., Yu, H., Zhang, J., Luo, X., Si, T.*, Liu,* C., Qiao,* Y. 2020. Machine learning for synthetic biology: Methods and applications Chinese Science Bulletin, 2020, 66(3), 284-299 (in Chinese)

23. Zhang, Y., He, D., Lu, H., Huang, J., Luo, X. 2020. Metabolic engineering of Saccharomyces cerevisiae chassis, Chinese Science Bulletin, 2020, 66(3), 310-318 (in Chinese)

22.  Tan, L., Zheng, Z., Xu, Y., Kong, W., Dai, Z., Qin, X., Liu, T., Tang, H. (2020). Efficient Selection Scheme for Incorporating Noncanonical Amino Acids Into Proteins in Saccharomyces cerevisiae. Frontiers in bioengineering and biotechnology, 8.

21. Tang, H., Wu, Y., Deng, J., Chen, N., Zheng, Z., Wei, Y., Luo, X. and Keasling, J.D., 2020. Promoter Architecture and Promoter Engineering in Saccharomyces cerevisiae. Metabolites, 10(8), p.320.

 

Before SIAT

2019
20. Luo, X.*; Reiter, M.A.*; d’Espaux, L.; Wong, J.; Denby, C.M.; Lechner, A.; Zhang, Y.; Grzybowski, A.T.; Harth, S.; Lin, W.; Lee, H.; Yu, C.; Shin, J.; Deng, K.; Benites, V.T.; Wang, G.; Baidoo, E.E.K.; Chen, Y.; Dev, I.; Petzold, C.J.; Keasling, J.D. “Complete biosynthesis of cannabinoids and their unnatural analogues in yeast”, Nature,2019, 567, 123. *Authors contributed equally

2018
19. Supekova, L.; Zambaldo, C.; Choi, S.; Lim, R.; Luo, X.; Kazane, S.A.; Young, T.S.; Schultz, P.G. “The genetic incorporation of p-azidomethyl-l phenylalanine into proteins in yeast”, Bioorg. Med. Chem. Lett. 2018, 28, 1570

18. Yang, P.-Y.; Zou, H.; Lee, C.; Muppidi, A.; Chao, E.; Fu, Q.; Luo, X.; Wang, D.; Schultz, P.G.; Shen, W. “A Stapled, Long-Acting Glucagon-like Peptide 2 Analog with Efficacy in Dextran Sodium Sulfate-Induced Mouse Colitis Models”, J. Med. Chem., 2018, 61, 3218.

2017
17. Du, J.; Cao, Y.; Liu, Y.; Wang, Y.; Zhang, Y.; Fu, G.; Zhang, Y.; Lu, L.; Luo, X.; Kim, C.H.; Schultz, P.G.; Wang. F. “Engineering Bifunctional Antibodies with Constant Region Fusion Architectures”, J. Am. Chem. Soc., 2017, 139, 18607

16. Zambaldo, C.; Luo, X.; Mehta, A.P.; Schultz, P.G. “Recombinant Macrocyclic Lanthipeptides Incorporating Non-Canonical Amino Acids”, J. Am. Chem. Soc. 2017, 139, 11646.

15. Luo, X.; Fu, G.; Wang, R.E.; Zhu, X.; Zambaldo, C.; Liu, R.; Liu, T.; Lyu, X.; Du, J.; Xuan, W.; Yao, A.; Reed, S.A.;Kang, M.; Zhang, Y.; Guo, H.; Huang, C.; Yang, P.-Y.; Wilson, I.A.; Schultz, P.G.; Wang, F. “Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria”, Nat. Chem. Biol. 2017, 13, 845.

14. Liu, T.; Jia, P.; Ma, H.; Reed, S.A.; Luo, X.; Larman, H.B.; Schultz, P.G. “Construction and Screening of a Lentiviral Secretome Library”, Cell. Chem. Biol. 2017, 24, 767.

2016
13. Wang, R.E.; Wang, Y.; Zhang, Y.; Gabrelow, C.; Zhang, Y.; Chi, V.; Fu, Q.; Luo, X.; Wang, D.; Joseph, S.; Johnson, K.; Chatterjee, A.K.; Wright, T.M.; Nguyen-Tran, V.T.B.; Teijaro, J.; Theofilopoulos, A.N.; Schultz, P.G.; Wang, F. “Rational design of a Kv1. 3 channel-blocking antibody as a selective immunosuppressant”, Proc.Nat. Acad. Sci. 2016, 113, 11501.

12. Luo, X.*; Wang, T.-S.A*; Zhang, Y.; Wang, F.; Schultz, P. G. “Stabilizing Protein Motifs with a Genetically Encoded Metal-Ion Chelator”, Cell. Chem. Biol., 2016, 23, 1098. *Authors contributed equally

11. Xuan, W.; Li, J.; Luo, X.; Schultz, P.G. “Genetic Incorporation of a Reactive Isothiocyanate Group into Proteins”, Angew. Chem. Int. Ed. 2016, 128, 10219.

10. Liu, T.; Wang, Y.; Luo, X.; Li, J.; Reed, S.A.; Xiao, H.; Young, T.S.; Schultz, P.G. “Enhancing protein stability with extended disulfide bonds” Proc. Nat. Acad. Sci. 2016, 113, 5910.

9. Cao, Y.; Rodgers, D.T.; Du, J.; Ahmad, I.; Hampton, E.N.; Ma, J.S.Y; Mazagova, M.; Choi, S.-H.; Yun, H.Y.; Xiao, H.; Yang, P.; Luo, X.; Lim, R.K.V.; Pugh, H.M.; Wang, F.; Kazane, S.A.; Wright, T.M.; Kim, C.H.; Schultz, P.G.; Young, T.S. “Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer”, Angew. Chem. Int. Ed. 2016, 128, 7646.

8. Yang, P.-Y.; Zou, H.; Chao, E.; Sherwood, L.; Nunez, V.; Keeney, M.; Ghartey-Tagoe, E.; Ding, Z.; Quirino, H.; Luo, X.; Welzel, G.; Chen, G.; Singh, P.; Woods, A.K.; Schultz, P.G.; Shen, W. “Engineering a long-acting, potent GLP-1 analog for microstructure-based transdermal delivery”, Proc. Nat. Acad. Sci. 2016, 113, 4140.

7. Luo, X.; Zambaldo, C.; Liu, T.; Zhang, Y.; Xuan, W.; Wang, C.; Reed, S.A.; Yang, P.Y.; Wang, R.E.; Javahishvili, T.; Schultz, P. G.; Young, T.S. “Recombinant Thiopeptides with Noncanonical Amino Acids”, Proc. Nat. Acad. Sci.2016, 113, 3615.

2015
6. Luo, X.*; Liu, T.*; Wang, Y.; Jia, H.; Zhang, Y.; Caballero, D.; Du, J.; Wang, R. E.; Wang, D.; Schultz, P. G.; Wang, F. “An Epitope-Specific Respiratory Syncytial Virus Vaccine based on an Antibody Scaffold”, Angew. Chem. Int. Ed. 2015, 54, 1. *Authors contributed equally

5. Harbut, M. B.; Vilchèze, C.; Luo, X.; Hensler, M. E.; Guo, H.; Yang, B.; Chatterjee, A. K.; Nizet, V.; Jacobs, W. R.; Schultz, P. G. “Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis”, Proc. Nat. Acad. Sci. 2015, 112, 4453.

4. Liu, T.; Du, J.; Luo, X.; Schultz, P. G.; Wang, F. “Homogeneously modified immunoglobulin domains for therapeutic application”, Curr. Opin. Chem. Biol. 2015, 28, 66.

3. Liu, T.; Fu, G.; Luo, X.; Liu, Y.; Wang, Y.; Wang, R. E.; Schultz, P. G.; Wang, F. “Rational Design of Antibody Protease Inhibitors”, J. Am. Chem. Soc. 2015, 137, 4042.

2. Wang, R. E.; Liu, T.; Wang, Y.; Cao, Y.; Du, J.; Luo, X.; Deshmukh, V.; Kim, C. H.; Lawson, B. R.; Tremblay, M. S.;Young, T.S.; Kazane, S.A.; Wang, F.; Schultz, P.G. “An Immunosuppressive Antibody–Drug Conjugate”, J. Am. Chem. Soc. 2015, 137, 3229.

1. Liu, T.; Zhang, Y.; Liu, Y.; Wang, Y.; Jia, H.; Kang, M.; Luo, X.; Caballero, D.; Gonzalez, J.; Sherwood, L.; Nunez,V.; Wang, D.; Woods, A.; Schultz, P.G.; Wang, F. “Functional human antibody CDR fusions as long-acting therapeutic endocrine agonists”, Proc. Nat. Acad. Sci. 2015, 112, 1356.

 

Patents

3. Keasling, Jay D., Leo D’espaux, Jeff Wong, L. U. O. Xiaozhou, Michael Reiter, Charles Denby, and Anna Lechner. “Methods for producing cannabinoids and cannabinoid derivatives.” U.S. Patent 10,975,379, issued April 13, 2021.

2. Keasling, J.D.; Luo, X. Microorganisms and methods for producing meroterpenoids. U.S. Provisional Patent,2017

1. Wang, F., Schultz, P.G., Luo, X.; Liu, T. Antigenic Fusion Proteins and Methods of Vaccination. U.S. Patent pending, 2015